<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with Wdesk from Workiva-->
<!--Copyright 2021 Workiva-->
<!--r:3abae60b-3479-49d3-bc3d-fc94d007b4b7,g:eae2f825-ccb7-4a71-98ed-18e82203704f-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.selectabio.com/role/CoverPageDocument" xlink:type="simple" xlink:href="selb-20210920.xsd#CoverPageDocument"/>
  <link:presentationLink xlink:role="http://www.selectabio.com/role/CoverPageDocument" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_dei_CoverAbstract_2cd17483-8e8f-4c51-b97b-b1d17d0ef27a" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_CoverAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_c34b3e90-4b6c-45eb-86f9-dd6964ce6aa0" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentType"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_2cd17483-8e8f-4c51-b97b-b1d17d0ef27a" xlink:to="loc_dei_DocumentType_c34b3e90-4b6c-45eb-86f9-dd6964ce6aa0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_0e3bcfbd-e2ea-4d26-b283-b002f26d9fd4" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentPeriodEndDate"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_2cd17483-8e8f-4c51-b97b-b1d17d0ef27a" xlink:to="loc_dei_DocumentPeriodEndDate_0e3bcfbd-e2ea-4d26-b283-b002f26d9fd4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_c54e1a7e-0b1e-4b96-bc80-4ede4b953d2f" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityRegistrantName"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_2cd17483-8e8f-4c51-b97b-b1d17d0ef27a" xlink:to="loc_dei_EntityRegistrantName_c54e1a7e-0b1e-4b96-bc80-4ede4b953d2f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_2004de67-c767-4c92-8a4a-12fba46bf5a9" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityIncorporationStateCountryCode"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_2cd17483-8e8f-4c51-b97b-b1d17d0ef27a" xlink:to="loc_dei_EntityIncorporationStateCountryCode_2004de67-c767-4c92-8a4a-12fba46bf5a9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_51cc7c0f-95ce-4e94-8b49-cb2d6d8c27a5" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityFileNumber"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_2cd17483-8e8f-4c51-b97b-b1d17d0ef27a" xlink:to="loc_dei_EntityFileNumber_51cc7c0f-95ce-4e94-8b49-cb2d6d8c27a5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_d0a56c15-00ec-43fd-8529-021700770a19" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityTaxIdentificationNumber"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_2cd17483-8e8f-4c51-b97b-b1d17d0ef27a" xlink:to="loc_dei_EntityTaxIdentificationNumber_d0a56c15-00ec-43fd-8529-021700770a19" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_4e3d8ba9-c0ea-4d54-8052-11b5e3d3ff3b" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityAddressAddressLine1"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_2cd17483-8e8f-4c51-b97b-b1d17d0ef27a" xlink:to="loc_dei_EntityAddressAddressLine1_4e3d8ba9-c0ea-4d54-8052-11b5e3d3ff3b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_38714d8a-2068-445f-a099-baaff7536956" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityAddressCityOrTown"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_2cd17483-8e8f-4c51-b97b-b1d17d0ef27a" xlink:to="loc_dei_EntityAddressCityOrTown_38714d8a-2068-445f-a099-baaff7536956" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince_cb28b3d8-2b8b-4a5e-88a8-3f4d78ac029b" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityAddressStateOrProvince"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_2cd17483-8e8f-4c51-b97b-b1d17d0ef27a" xlink:to="loc_dei_EntityAddressStateOrProvince_cb28b3d8-2b8b-4a5e-88a8-3f4d78ac029b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_597e6b3e-31a8-44ae-81d2-69e380b29c07" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityAddressPostalZipCode"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_2cd17483-8e8f-4c51-b97b-b1d17d0ef27a" xlink:to="loc_dei_EntityAddressPostalZipCode_597e6b3e-31a8-44ae-81d2-69e380b29c07" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_5839962c-147c-4c1c-84ac-4897a325b144" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_CityAreaCode"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_2cd17483-8e8f-4c51-b97b-b1d17d0ef27a" xlink:to="loc_dei_CityAreaCode_5839962c-147c-4c1c-84ac-4897a325b144" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_8706dffc-e4a5-477c-b1ab-84785d1c15d9" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_LocalPhoneNumber"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_2cd17483-8e8f-4c51-b97b-b1d17d0ef27a" xlink:to="loc_dei_LocalPhoneNumber_8706dffc-e4a5-477c-b1ab-84785d1c15d9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_WrittenCommunications_72174a8b-4941-414c-a00c-277f1901aafe" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_WrittenCommunications"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_2cd17483-8e8f-4c51-b97b-b1d17d0ef27a" xlink:to="loc_dei_WrittenCommunications_72174a8b-4941-414c-a00c-277f1901aafe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SolicitingMaterial_663c575e-28b3-43d8-9c32-a3c3d42ec978" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_SolicitingMaterial"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_2cd17483-8e8f-4c51-b97b-b1d17d0ef27a" xlink:to="loc_dei_SolicitingMaterial_663c575e-28b3-43d8-9c32-a3c3d42ec978" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementTenderOffer_33884721-d511-43e9-8b7c-896b34c25bd8" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_PreCommencementTenderOffer"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_2cd17483-8e8f-4c51-b97b-b1d17d0ef27a" xlink:to="loc_dei_PreCommencementTenderOffer_33884721-d511-43e9-8b7c-896b34c25bd8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementIssuerTenderOffer_a37823a5-17c9-43ba-85d9-d768e529b969" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_PreCommencementIssuerTenderOffer"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_2cd17483-8e8f-4c51-b97b-b1d17d0ef27a" xlink:to="loc_dei_PreCommencementIssuerTenderOffer_a37823a5-17c9-43ba-85d9-d768e529b969" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_de69e99d-fdd4-438c-9d38-c4a66925a92e" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_Security12bTitle"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_2cd17483-8e8f-4c51-b97b-b1d17d0ef27a" xlink:to="loc_dei_Security12bTitle_de69e99d-fdd4-438c-9d38-c4a66925a92e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_b1a56dbe-419d-4c24-9b17-3df32ea5d597" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_TradingSymbol"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_2cd17483-8e8f-4c51-b97b-b1d17d0ef27a" xlink:to="loc_dei_TradingSymbol_b1a56dbe-419d-4c24-9b17-3df32ea5d597" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName_d70b19f5-caf3-4920-b90c-987e3068453e" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_SecurityExchangeName"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_2cd17483-8e8f-4c51-b97b-b1d17d0ef27a" xlink:to="loc_dei_SecurityExchangeName_d70b19f5-caf3-4920-b90c-987e3068453e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_cc2db9c6-5a66-4318-87b1-124c33da5f37" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityEmergingGrowthCompany"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_2cd17483-8e8f-4c51-b97b-b1d17d0ef27a" xlink:to="loc_dei_EntityEmergingGrowthCompany_cc2db9c6-5a66-4318-87b1-124c33da5f37" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityExTransitionPeriod_8562924f-5a16-43e2-ba78-5bd889673d48" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityExTransitionPeriod"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_2cd17483-8e8f-4c51-b97b-b1d17d0ef27a" xlink:to="loc_dei_EntityExTransitionPeriod_8562924f-5a16-43e2-ba78-5bd889673d48" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_03d9a3a4-e99a-4475-8000-3ecc2396ffaa" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityCentralIndexKey"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_2cd17483-8e8f-4c51-b97b-b1d17d0ef27a" xlink:to="loc_dei_EntityCentralIndexKey_03d9a3a4-e99a-4475-8000-3ecc2396ffaa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_444bf2cc-a002-4ea8-bdca-4207c49e6dfc" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_AmendmentFlag"/>
    <link:presentationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_2cd17483-8e8f-4c51-b97b-b1d17d0ef27a" xlink:to="loc_dei_AmendmentFlag_444bf2cc-a002-4ea8-bdca-4207c49e6dfc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
</link:linkbase>
