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Disclosure - Net Loss Per Share Allocable to Common Stockholders - Schedule of Computation of Basic and Diluted Net Loss Per Share Allocable to Common Stockholders (Details) link:presentationLink link:calculationLink link:definitionLink 9955534 - Disclosure - Net Loss Per Share Allocable to Common Stockholders - Schedule of Potential Dilutive Shares of Common Stock Excluded from the Computation of the Diluted Net Loss Per Share Allocable to Common Stockholders (Details) link:presentationLink link:calculationLink link:definitionLink 9955535 - Disclosure - Fair Value Measurements - Schedule of Assets and Liabilities Measured at Fair Value on a Recurring Basis (Details) link:presentationLink link:calculationLink link:definitionLink 9955536 - Disclosure - Fair Value Measurements - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955537 - Disclosure - Fair Value Measurements - Schedule of Cash, Cash Equivalents, and Restricted Cash (Details) link:presentationLink link:calculationLink link:definitionLink 9955538 - Disclosure - Fair Value Measurements - Schedule of Fair Value Measurement Inputs and Valuation Techniques for Warrants Liability (Details) link:presentationLink link:calculationLink link:definitionLink 9955539 - Disclosure - Fair Value Measurements - Schedule of Roll-Forward of Fair Value for the Company’s Level 3 Warrant Liabilities and CVR Liability (Details) link:presentationLink link:calculationLink link:definitionLink 9955540 - Disclosure - Fair Value Measurements - Schedule of Fair Value Measurement Inputs and Valuation Techniques for CVR Liability (Details) link:presentationLink link:calculationLink link:definitionLink 9955541 - Disclosure - Fair Value Measurements - Schedule of Roll-Forward of Fair Value for the Forward Contract Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955542 - Disclosure - Property and Equipment - Schedule of Property and Equipment (Details) link:presentationLink link:calculationLink link:definitionLink 9955543 - Disclosure - Property and Equipment - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955544 - Disclosure - Accrued Expenses (Details) link:presentationLink link:calculationLink link:definitionLink 9955545 - Disclosure - Leases - 7495 New Horizon Way Leases (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 9955546 - Disclosure - Leases - 65 Grove Street Lease (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 9955547 - Disclosure - Leases - 704 Quince Orchard Road Leases (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 9955548 - Disclosure - Leases - Moscow, Russia Lease (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 9955549 - Disclosure - Leases - Schedule of Components of Lease Costs (Details) link:presentationLink link:calculationLink link:definitionLink 9955550 - Disclosure - Leases - Schedule of Maturity of Operating Lease Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955550 - Disclosure - Leases - Schedule of Maturity of Operating Lease Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955551 - Disclosure - Leases - Schedule of Supplemental Disclosure for the Statement of Cash Flows Related to Operating Leases (Details) link:presentationLink link:calculationLink link:definitionLink 9955552 - Disclosure - Leases - Schedule of Additional Information Related to Operating Leases (Details) link:presentationLink link:calculationLink link:definitionLink 9955553 - Disclosure - Debt (Details) link:presentationLink link:calculationLink link:definitionLink 9955554 - Disclosure - Convertible Preferred Stock - Series B Preferred Stock (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 9955555 - Disclosure - Convertible Preferred Stock - Series A Preferred Stock (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 9955556 - Disclosure - Convertible Preferred Stock - Conversion (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 9955557 - 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Equity - June 2020 Sobi Stock Purchase (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 9955565 - Disclosure - Equity - December 2019 Financing (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 9955566 - Disclosure - Equity - Schedule of Warrant Activity (Details) link:presentationLink link:calculationLink link:definitionLink 9955567 - Disclosure - Equity - Common Stock (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 9955568 - Disclosure - Equity - Schedule of Authorized Shares of Common Stock for Future Issuance (Details) link:presentationLink link:calculationLink link:definitionLink 9955569 - Disclosure - Stock Incentive Plans - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955570 - Disclosure - Stock Incentive Plans - Schedule of Stock-Based Compensation Expense (Details) link:presentationLink link:calculationLink link:definitionLink 9955571 - Disclosure - Stock Incentive Plans - Schedule of Weighted Average Assumptions Used (Details) link:presentationLink link:calculationLink link:definitionLink 9955572 - Disclosure - Stock Incentive Plans - Schedule of Stock Option Activity (Details) link:presentationLink link:calculationLink link:definitionLink 9955573 - Disclosure - Stock Incentive Plans - Schedule of Restricted Stock Units Activity (Details) link:presentationLink link:calculationLink link:definitionLink 9955574 - Disclosure - Revenue Arrangements - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955575 - Disclosure - Revenue Arrangements - Schedule of Changes in Contract Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955576 - Disclosure - Related-party Transactions - Schedule of Related Party Transactions (Details) link:presentationLink link:calculationLink link:definitionLink 9955577 - Disclosure - Related-Party Transactions - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955578 - Disclosure - Collaboration and License Agreements - Biogen M.A., Inc. (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 9955579 - Disclosure - Collaboration and License Agreements - National Cancer Institute of the National Institutes of Health (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 9955580 - Disclosure - Collaboration and License Agreements - Ginkgo Bioworks Holdings, Inc. (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 9955581 - Disclosure - Collaboration and License Agreements - Genovis AB (publ.) (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 9955582 - Disclosure - Collaboration and License Agreements - Cyrus Biotechnology, Inc. (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 9955583 - Disclosure - Collaboration and License Agreements - Asklepios Biopharmaceutical, Inc. (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 9955584 - Disclosure - Collaboration and License Agreements - Shenyang Sunshine Pharmaceutical Co., Ltd (Narrative) (Details) link:presentationLink link:calculationLink link:definitionLink 9955585 - Disclosure - Income Taxes - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955586 - Disclosure - Income Taxes - Schedule of Effective Income Tax Rate Reconciliation (Details) link:presentationLink link:calculationLink link:definitionLink 9955587 - Disclosure - Income Taxes - Schedule of Deferred Tax Assets and Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955588 - Disclosure - Employee Benefit Plans (Details) link:presentationLink link:calculationLink link:definitionLink 9955589 - Disclosure - Restructuring - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955590 - Disclosure - Restructuring - Schedule of Change in Accrued Restructuring Balance (Details) link:presentationLink link:calculationLink link:definitionLink 9955591 - Disclosure - Segment Reporting (Details) link:presentationLink link:calculationLink link:definitionLink